Endoscopists prefer Propofol
In a recent study which directly compared balanced propofol sedation (BPS; propofol in combination with midazolam and meperidine) with conventional sedation (midazolam and meperidine), BPS appeared to provide higher health care satisfaction and greater patient cooperation, with a similar profile for adverse events. The latest study is just one of many that demonstrate propofol to be either equivalent to or better than benzodiazepines for endoscopic sedation.
Outcomes did not differ significantly between the two groups in terms of mean duration of induction, procedure or recovery. Likewise, there were no significant differences in rates of cardiopulmonary complications, or transient interruption of procedures.
Post-procedure surveys of the endoscopists and nurses indicated a significantly higher level of health care provider satisfaction and patient cooperation in the BPS group than in the conventional group. Patient assessment was similar in the two groups, but patients in the BPS arm had less memory of endoscope insertion and withdrawal than those in the conventional group. The authors concluded that the data support the use of endoscopist-directed BPS for therapeutic endoscopy.