USA study of capsule endoscopy and IBD management

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A recent study has evaluated the impact of capsule endoscopy on the management of inflammatory bowel disease (IBD)

A retrospective cohort study was performed of all capsule endoscopies for IBD at a tertiary care center from 2003–2009.Dr Millie Long and colleagues from North Carolina, USA defined the results of capsule endoscopy in subtypes of IBD, and determined whether capsule endoscopy results in management changes.

Descriptive statistics were used to compare IBD-specific medications, surgeries, and imaging studies in the 3 months prior and 3 months after capsule endoscopy.
Of the 907 capsule endoscopies performed from 2003–2009, 128 were for an indication of symptomatic IBD and 124 capsules left the stomach.

For more information about our community endoscopy services please click hereThe team found that only 22% of capsule endoscopies carried out for Crohn’s disease were normal, compared to 53% for indeterminate colitis, and 35% for pouchitis.
62% of the patients with Crohn’s disease had a change in medication in the 3 months after the capsule endoscopy, with 40% initiating a new IBD medication, most commonly budesonide or corticosteroids.
13% of patients with Crohn’s disease also underwent surgery in the 3 months following capsule endoscopy.
The research team noted that the severe findings on capsule endoscopy in patients with Crohn’s disease, as compared to no/minimal findings, resulted in significant differences in medication changes, addition of medications, and surgeries.
Dr Long’s team commented, “Capsule endoscopy results in management changes in the majority of cases of symptomatic IBD, regardless of the subtype of IBD.”